Male provider reading a medical textbook at his deck.

Review evidence-based treatment options for common medical and behavioral health conditions. Clinical practice guidelines are resources* for Humana-participating physicians and other Humana-contracted healthcare professionals. 

Guidelines adopted by Humana

Anxiety

Children and adolescents
American Academy of Child and Adolescent Psychiatry
Clinical Practice Guideline for the Assessment and Treatment of Children and Adolescents With Anxiety Disorders, 2020

Adults
American Academy of Family Physicians
Generalized Anxiety Disorders and Panic Disorder in Adults 2022

Attention deficit/hyperactivity disorder

Attention deficit/hyperactivity disorder
American Academy of Family Physicians
Attention Deficit/Hyperactivity Disorder: AAP Updates for Diagnosis and Management, 2020

Attention deficit hyperactivity disorder
American Academy of Pediatrics
Clinical Practice Guideline for the Diagnosis, Evaluation, and Treatment of Attention-Deficit/Hyperactivity Disorder in Children and Adolescents, 2019

Children with autism spectrum disorder

Autism spectrum disorder
American Academy of Pediatrics
Identification, Evaluation, and Management of Children With Autism Spectrum Disorder, 2020

Back pain

Back pain
Department of Veterans Affairs Department of Defense (VA/DoD)
VA/DoD Clinical Practice Guideline for the Diagnosis and Treatment of Low Back Pain, 2022

Behavior or conduct problems in children

Behavior or conduct problems in children (Oppositional Defiant Disorder)
Centers for Disease Control and Prevention: (CDC):
Behavior or Conduct Problems in Children, 2023

Bipolar disorder in adults

Bipolar disorder in adults
Department of Veterans Affairs/Department of Defense
Management of Bipolar disorder in Adults, 2023

Cardiovascular

ASCVD Risk Estimator Plus
American College of Cardiology (ACC)
ASCVD Risk Estimator Plus, 2024

Atrial fibrillation
National Institute for Health and Care Excellence (NICE)
Atrial fibrillation: diagnosis and management (2021)

Heart failure
American Heart Association/American College of Cardiology/Heart Failure Society of America
2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines

Cardiovascular disease and stroke
American College of Cardiology (ACC)/American Heart Association (AHA) Task Force on Clinical Practice Guidelines
ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines, 2019

Valvular heart disease
American College of Cardiology/American Association Joint Committee on Clinical Practice Guidelines
ACC/AHA Guideline for the Management of Patients with Valvular Heart Disease, 2020

Cholesterol treatment

Cholesterol Management 
Department of Veterans Affairs Department of Defense (VA/DoD)
VA/DoD Clinical Practice Guideline: The Management of Dyslipidemia for Cardiovascular Risk Reduction (2020)

COVID-19

COVID-19 
Infectious Diseases Society of America (IDSA) (New July 2024)
IDSA Guidelines on the Treatment and Management of Patients with COVID-19, 2024 

Depression

Adolescents
American Academy of Pediatrics (AAP)
American Academy of Pediatrics Part 1 Guideline for Adolescent Depression in Primary Care (GLAD-PC), 2018
American Academy of Pediatrics Part 2 Guideline for Adolescent Depression in Primary Care (GLAD-PC), 2018

Depression in Primary Care (adults)
Department of Veterans Affairs Department of Defense (VA/DoD)
Managing Depression in Primary Care, 2020

Depression across three age cohorts
American Psychological Association
APA Clinical Practice Guideline for the Treatment of Depression Across Three Age Cohorts, 2019 

Diabetes

Diabetes
American Diabetes Association (ADA)
American Diabetes Association Standards of Medical Care in Diabetes, 2025

Fall prevention

Fall prevention
The Task Force on Global Guidelines for Falls in Older Adults
World Guidelines for Falls Prevention and Management for Older Adults: A Global Initiative, 2022

Headache/migraine

Headache/migraine
Department of Veterans Affairs/Department of Defense (VA/DoD)
VA/DoD Clinical Practice Guideline: Management of Headache, 2023

Human Immunodeficiency Virus (HIV)

HIV
HIV.gov
Adult and Adolescent Antiretroviral Agents
Adult and Adolescent Opportunistic Infections
Pediatric Antiretroviral Agents
Pediatric Opportunistic Infections
Perinatal HIV Guidelines
Caring for Persons with HIV in a disaster area
Guidance for COVID-19 and people with HIV
2024

Hypertension

Hypertension
American College of Cardiology/American Heart Association/European Society of Cardiology/European Society of Hypertension Blood Pressure
Harmonization of the American College of Cardiology/American Heart Association and European Society of Cardiology /European Society of Hypertension Blood Pressure/Hypertension Guidelines: Comparisons, Reflections, and Recommendations, 2022 

Immunizations

Childhood immunizations
Centers for Disease Control and Prevention (CDC)
Vaccines for Your Children

Adult immunizations
Centers for Disease Control and Prevention (CDC)
Vaccine information for adults

Incontinence urinary

Women
Journal of Women’s Health
Female Urinary Incontinence Evidence-Based Treatment Pathways: An Infographic for shared decision-making, 2022 

Men
National Institute for Health and Care Excellence (NICE)
Lower Urinary Tract Symptoms in Men, 2015

Kidney disease

Kidney disease
National Kidney Foundation (NKF)
Kidney Disease Outcomes Quality Initiative (KDOQI) Guidelines/Commentaries
Evidence-based clinical practice guidelines for all stages of chronic kidney disease, 2024

Please note: The National Kidney Foundation (NKF) is the copyright holder and owner of all content, videos, and images. As such, the NKF hereby grants permission to Humana to use NKF guidelines on Kidney Disease Outcomes Quality Initiative Clinical Practice Guidelines to place on the company's website on Clinical Practice Guidelines for their providers. NKF is providing permission for Humana to be able to link to the NKF guideline at www.ajkd.org/content/kdoqiguidelines . NKF gives copyright permission for the use of the above guidelines content only and no use of other NKF images, charts, graphs or content. Produced by the National Kidney Foundation, Inc. All rights reserved.

Obsessive Compulsive Disorders (OCDs)

Obsessive Compulsive Disorder  
American Psychiatric Association: (APA)

Practice Guideline for the Treatment of Patients with Obsessive Compulsive Disorder, 2007

Guideline Watch Practice Guideline for the Treatment of Patients with Obsessive-Compulsive Disorder, 2013

Treating Obsessive Compulsive Disorder a Quick Reference Guide, 2007

Opioids

Opioid prescribing
Centers for Disease Control and Prevention (CDC)
CDC Clinical Practice Guideline for Prescribing Opioids for Pain (CDC), 2022

Dosage reduction
Health and Human Services (HHS) 
HSS Guide for Clinicians on the Appropriate Dosage Reduction or Discontinuation of Long-Term Opioid Analgesics, 2019

Use in pregnancy
American College of Obstetricians and Gynecologists
Opioid Use and Opioid Use Disorder in Pregnancy, 2021

Oxygen therapy

Adults
American Thoracic Society (ATS)
Home Oxygen Therapy for Adults with Chronic Lung Disease. An Official American Thoracic Society Clinical Practice Guideline, 2020

Reprinted with permission of the American Thoracic Society.
Copyright ©2024 American Thoracic Society. All rights reserved.
Cite: Susan S. Jacobs, Jerry A Krishnan, David J Lederer, Marya Ghazipura, Tanzib Hossain, Ai-Yui M. Tan, Brain Carlin, M. Bradley Drummond, Magnus Ekstrőm, Chris, Garvey, Bridget A. Graney, Beverly Jackson, Thomas Kallstrom, Shandra L. Knight, Kathleen Lindell, Valentin Prieto-Centurion, Elissabetta A. Renzoni, Christopher J. Ryerson, Ann Schneidman, Jeffrey Swigris, Dona Upson, Anne E Holland,/2020/American Journal of Respiratory and Critical Care Medicine/Volume 202/Issue 10/e121-e141
The American Journal of Respiratory and Critical Care Medicine is an official journal of the American Thoracic Society.

Children
American Thoracic Society (ATS)
Home Oxygen Therapy for Children. An Official American Thoracic Society Clinical Practice Guideline, 2018

Reprinted with permission of the American Thoracic Society.
Copyright ©2024 American Thoracic Society. All rights reserved.
Cite: Don Hayes Jr., Kevin C. Wilson, Katelyn Kirvchenia, Stephen M.M. Hawkins, Ian M. Balfour-Lynn, David Gozal, Howard B. Panitch, Mark L. Splaingard, Lawrence M. Rhein, Geoffrey Kurland, Steven H. Abman, Timothy M. Hoffman, Christopher L. Carrol, Mary E. Cataletto, Dmitry Tumin, Eyal Oren, Richard J. Martin, Joyce Baker, Gregory R. Porta, Deborah Kaley, Ann Gettys, Robin R. Deterding, /2018/American Journal of Respiratory and Critical Care Medicine/Volume 199/Issue 3/e5-e23
The American Journal of Respiratory and Critical Care Medicine is an official journal of the American Thoracic Society.

Palliative care

Palliative care
National Coalition for Hospice and Palliative Care
Clinical Practice Guidelines for Quality Palliative Care, 4th edition, 2018

Post-traumatic stress disorder

Post-traumatic stress disorder
Department of Veterans Affairs/Department of Defense
Post-traumatic stress disorder, 2023

Perinatal guidelines (New July 2024)

Department of Veterans Affairs/Department of Defense (VA/DoD)
Management of post-traumatic stress disorder and acute stress disorder, 2023

Pregnancy

Pregnancy
Department of Veterans Affairs/Department of Defense (VA/DoD)
VA/DoD Clinical Practice Guidelines for the Management of Pregnancy, 2023

 

Preventive services

Children
American Academy of Pediatrics (AAP)
Recommendations for Preventive Pediatric Health Care – Bright Futures Periodicity Table, 2024

All Ages (USPSTF)
United States Preventive Services Task Force (USPSTF)
USPSTF Guidelines – All Topics, 2024

Well-Women routine care
Well Women
The American College of Obstetricians and Gynecologists (ACOG)
Recommendations for Well-Woman Care, 2024

Respiratory

Asthma
GINA © 2024 Global Initiative for Asthma, reprinted with permission. Available from www.ginasthma.org
2024 Global Strategy for Asthma Management and Prevention, 2024

Chronic Obstructive Pulmonary Disease (COPD)
Global Initiative for Chronic Obstructive Lung Disease (GOLD)
© 2024, Global Initiative for Chronic Obstructive Lung Disease, available from www.goldcopd.org , published in Deer Park, IL, USA.
Global Strategy for the Prevention, Diagnosis and Management of COPD, 2025 Report

Schizophrenia

Schizophrenia
Department of Veterans Affairs/Department of Defense (VA/DoD)
Management of First-Episode Psychosis and Schizophrenia 2023

Sickle cell anemia

Sickle cell anemia 
American Society of Hematology
Clinical Practice Guidelines on Sickle Cell, 2024

 

 

Sleep apnea

Sleep apnea
American Society of Anesthesiologists Task Force on Perioperative Management of Patients with Obstructive Sleep Apnea
Practice Guidelines for the Perioperative Management of Patients with Obstructive Sleep Apnea, 2014 

Sleep/insomnia

Sleep/Insomnia
Department of Veterans Affairs/Department of Defense (VA/DoD)
VA/DoD Clinical Practice Guidelines for the Management of Chronic Insomnia Disorder and Obstructive Sleep Apnea (Insomnia/OSA), 2019 

Substance use disorders

Adults

Department of Veterans Affairs/ Department of Defense
Substance use Disorders in Adults, 2021

Suicide

Youth suicide prevention
American Academy of Pediatrics
Primary and Secondary Prevention of Youth Suicide, 2020

Adults
Department of Veterans Affairs/Department of Defense
Assessment and Management of Patients at Risk for Suicide 2019

Syphilis (including congenital syphilis)

Syphilis
Centers for Disease Control and Prevention (CDC)
Sexually Transmitted Infections Treatment Guidelines: Syphilis, 2021

Telehealth

Telehealth
American Medical Association (AMA)
Digital health implementation playbook series, 2024

Transgender

ACOG Statement 
American College of Obstetricians and Gynecologists (ACOG)
ACOG Committee Opinion Health Care for Transgender and Gender Diverse Individuals, 2024

Standard of care
World Professional Association for Transgender Health (WPATH)
Standards of Care for the Health of Transgender and Gender Diverse People, Version 8, 2023

Psychological care
American Psychological Association
APA Guidelines for Psychological Practice with Sexual Minority Persons, 2021

Humana periodically monitors compliance with nationally recognized clinical practice guidelines.

*Humana publishes medical guidelines from a number of well-respected national sources. These guidelines may have some differences in recommendations. Information contained in the guidelines is not a substitute for a physician’s or other healthcare professional's clinical judgment and is not always applicable to an individual. Therefore, the physician or healthcare professional and patient should work in partnership in the decision-making process regarding the patient's treatment. Furthermore, using this information will not guarantee a specific outcome for each patient. None of the information in the guidelines is intended to interfere with or prohibit clinical decisions made by a treating physician or other healthcare professional regarding medically available treatment options for patients.

Publication of these guidelines is not a promise or guarantee of coverage. Individuals should review their coverage to determine benefits.

Links to other websites are provided for your convenience only and do not constitute or imply endorsement by Humana of these sites, products or services described on these sites, or of any other material contained therein. Humana disclaims responsibility for their content and accuracy.

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